Article
In vivo and in vitro studies of Chlamydia trachomatis TrpR:DNA interactions.
Molecular microbiology - 1 Mar 2006
Carlson John H, Wood Heidi, Roshick Christine, Caldwell Harlan D, McClarty Grant
Abstract excerpt
We previously reported that Chlamydia trachomatis expresses the genes encoding tryptophan synthase (trpBA) and the tryptophan repressor (trpR). Here we employ primer extension analysis to identify the transcriptional origins of both trpR and trpBA, allowing for the identification of the putative operator sequences for both trpR and trpBA. Moreover we demonstrate that native recombinant chlamydial TrpR binds to...
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