Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A common haplotype of protamine 1 and 2 genes is associated with higher sperm counts.

International journal of andrology - 1 Feb 2010

Tüttelmann F, Krenková P, Römer S, Nestorovic A R, Ljujic M, Stambergová A, Macek M, Macek M, Nieschlag E, Gromoll J, Simoni M

Abstract excerpt

Sperm chromatin compaction in the sperm head is achieved when histones are replaced by protamines during spermatogenesis. Haploinsufficiency of the protamine 1 (PRM1) or PRM2 gene causes infertility in mice. However, the published data remain inconclusive about a role of PRM1/2 variants in male i...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Protamines
Share to Chromatin
Share to Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histones

Share to Infertility, Male

Share to Spermatogenesis

Share to Spermatozoa

Source

Identifiers

PMID: 19863670
DOI: 10.1111/j.1365-2605.2009.01003.x

Genes

PRM1
PRM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19863670-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A common haplotype of protamine 1 and 2 genes is associated with higher sperm counts.PMID 19863670Read ↗

Protamine-1 and -2 polymorphisms and gene expression in male infertility: an Italian study.Semantic proximity Read ↗

A common protamine 1 promoter polymorphism (-190 C->A) correlates with abnormal sperm morphology and increased protamine P1/P2 ratio in infertile patients.Semantic proximity Read ↗

The aetiology of sperm protamine abnormalities and their potential impact on the sperm epigenome.Semantic proximity Read ↗

PRM1 variant rs35576928 (Arg>Ser) is associated with defective spermatogenesis in the Chinese Han population.Semantic proximity Read ↗

An SNP in protamine 1: a possible genetic cause of male infertility?Semantic proximity Read ↗

The c.-190 C>A transversion in promoter region of protamine1 gene as a genetic risk factor for idiopathic oligozoospermia.Semantic proximity Read ↗

The Clinical Utility of the Protamine 1/Protamine 2 Ratio in SpermSemantic proximity Read ↗

Mutations in the protamine 1 gene associated with male infertilitySemantic proximity Read ↗

Protamine alterations in human spermatozoa.Semantic proximity Read ↗

Evaluation of protamines 1 and 2 transcript contents in spermatozoa from asthenozoospermic men.Semantic proximity Read ↗

Aberrant protamine content in sperm and consequential implications for infertility treatment.Semantic proximity Read ↗

Haploinsufficiency of protamine-1 or -2 causes infertility in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.