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Article

Evaluation of protamines 1 and 2 transcript contents in spermatozoa from asthenozoospermic men.

1 Jan 2007

Abstract excerpt

During mammalian spermatogenesis, the chromatin structure undergoes substantial condensation. The key role in this process is played by protamines 1 and 2 (PRM1, PRM2). We attempted to compare the levels of PRM1 and PRM2 transcripts in mature spermatozoa of normospermic and asthenozoospermic men. Human ejaculates from normozoospermic (n=70) and asthenozoospermic (n=100) donors were purified by centrifugation...

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PMID: 18292846
DOI: 10.2478/4498

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