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Article

UGT1A1 promoter genotype is not strongly associated with severity of coronary artery disease.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Dec 2009

Papez Michael J, Civalier Chris J, Thorne Leigh B, Gulley Margaret L

Abstract excerpt

Atherosclerosis is a leading cause of morbidity and mortality. Oxidative stress is thought to play a role in its pathogenesis. Bilirubin is an endogenous antioxidant that is mildly elevated in people with Gilbert syndrome. Homozygosity for a A(TA)7TAA variant of the UDP-glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1) promoter is necessary for expression of the Gilbert phenotype. We studied the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19861894
DOI: 10.1097/PDM.0b013e3181a23bbc

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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