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Article

Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms.

Human molecular genetics - 15 Jan 2010

van der Harst Pim, Bakker Stephan J L, de Boer Rudolf A, Wolffenbuttel Bruce H R, Johnson Toby, Caulfield Mark J, Navis Gerjan

Abstract excerpt

Uric acid (UA) is the final catabolic product of purine metabolism and elevated levels are associated with diabetes and cardiovascular disease. A recent meta-analysis of genome-wide association studies totalling 28,141 participants identified five novel loci associated with serum UA levels. In ou...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19861489
DOI: 10.1093/hmg/ddp489

Genes

GCKR
CRP
PDZK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19861489-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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