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Article

No evidence for glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 in breast cancer risk.

Breast cancer research and treatment - 1 Jun 2010

Andonova Irena E, Justenhoven Christina, Winter Stefan, Hamann Ute, Baisch Christian, Rabstein Sylvia, Spickenheuer Anne, Harth Volker, Pesch Beate, Brüning Thomas, Ko Yon-Dschun, Ganev Varban, Brauch Hiltrud

Abstract excerpt

Breast cancer is a complex disease and in recent years a number of breast cancer susceptibility genes have been identified, but the role of low penetrance susceptibility genes has not been completely resolved. Glutathione S-transferases (GSTs) are phase II xenobiotic metabolizing enzymes involved in the detoxification of chemical carcinogens and environmental pollutants and play an important role in cell defense...

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Source

Identifiers

PMID: 19859803
DOI: 10.1007/s10549-009-0589-5

Genes

GSTA2
GSTM2
GSTO1
GSTO2
GSTZ1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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No evidence for glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 in breast cancer risk.PMID 19859803Read ↗

Polymorphisms in GSTT1 and GSTM1 genes as possible risk factors for susceptibility to breast cancer development and their influence in chemotherapy response: a systematic review.Semantic proximity Read ↗

Role of glutathione S-transferase omega gene polymorphisms in breast-cancer risk.Semantic proximity Read ↗

The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.Semantic proximity Read ↗

Glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) variants and breast cancer risk in Burkina Faso.Semantic proximity Read ↗

Evaluation of molecular markers GSTM1 and GSTT1 and clinical factors in breast cancer: case-control study and literature review.Semantic proximity Read ↗

Glutathione S-transferases M1, T1, and P1 and breast cancer: a pooled analysis.Semantic proximity Read ↗

Meta-analysis of genetic polymorphisms in xenobiotic metabolizing enzymes and their association with breast cancer risk.Semantic proximity Read ↗

Genetic polymorphisms in Glutathione S-transferase Omega (GSTO) and cancer risk: a meta-analysis of 20 studies.Semantic proximity Read ↗

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?Semantic proximity Read ↗

Susceptibility to breast cancer and three polymorphisms of GSTZ1.Semantic proximity Read ↗

Polymorphisms of glutathione S-transferase A1 and O1 and breast cancer among postmenopausal Danish women.Semantic proximity Read ↗

Glutathione-S-transferase M1, T1 and P1 polymorphisms, and breast cancer risk, in BRCA1/2 mutation carriers.Semantic proximity Read ↗

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