Article
Susceptibility to breast cancer and three polymorphisms of GSTZ1.
DNA and cell biology - 1 Mar 2012
Saadat Iraj, Khalili Maryam, Nafissi Samane, Omidvari Shahpour, Saadat Mostafa
Abstract excerpt
Glutathione S-transferases class zeta (GSTζ) is involved in the detoxification of xenobiotic compounds and catalyzes the biotransformation of a variety of α-haloacids including dichloroacetic acid and chlorofluoroacetic acid. It has been reported that, in mice, deficiency of Gstz1 (a member of GSTζ) resulted in the generation of a constant level of oxidative stress. The present study was carried out to...
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