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Article

The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.

Oncology reports - 1 Sept 2009

Silva Susana N, Azevedo Ana Paula, Teixeira Valdemar, Pina Julieta Esperança, Rueff José, Gaspar Jorge Francisco

Abstract excerpt

Glutathione-S-transferases (GSTs) are a super-family of phase II metabolizing enzymes that catalyse the detoxification of a large range of endogenous and exogenous toxic compounds, playing an important role in protecting cells against damage, through glutathione conjugation with electrophilic sub...

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Source

Identifiers

PMID: 19639209
DOI: 10.3892/or_00000477

Genes

GSTA2
GSTA1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19639209-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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The role of GSTA2 polymorphisms and haplotypes in breast cancer susceptibility: a case-control study in the Portuguese population.PMID 19639209Read ↗

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Glutathione S-transferase M1, T1, and P1 genotypes and breast cancer risk: a study in a Portuguese population.Semantic proximity Read ↗

Polymorphisms in GSTT1 and GSTM1 genes as possible risk factors for susceptibility to breast cancer development and their influence in chemotherapy response: a systematic review.Semantic proximity Read ↗

Genetic polymorphisms in oestrogen metabolic pathway and breast cancer: a positive association with combined CYP/GST genotypes.Semantic proximity Read ↗

Do single nucleotide polymorphisms in xenobiotic metabolizing genes determine breast cancer susceptibility and treatment outcomes?Semantic proximity Read ↗

The Role of Glutathione Transferase Omega-Class Variant Alleles in Individual Susceptibility to Ovarian Cancer.Semantic proximity Read ↗

No evidence for glutathione S-transferases GSTA2, GSTM2, GSTO1, GSTO2, and GSTZ1 in breast cancer risk.Semantic proximity Read ↗

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Meta-analysis of genetic polymorphisms in xenobiotic metabolizing enzymes and their association with breast cancer risk.Semantic proximity Read ↗

Evaluation of molecular markers GSTM1 and GSTT1 and clinical factors in breast cancer: case-control study and literature review.Semantic proximity Read ↗

The Association between Gene-Environment Interactions and Diseases Involving the Human GST Superfamily with SNP Variants.Semantic proximity Read ↗

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