Article
Approaches to identify genes for complex human diseases: lessons from Mendelian disorders.
Human mutation - 1 Oct 2003
Dean Michael
Abstract excerpt
The focus of most molecular genetics research is the identification of genes involved in human disease. In the 20th century, genetics progressed from the rediscovery of Mendel's Laws to the identification of nearly every Mendelian genetic disease. At this pace, the genetic component of all complex human diseases could be identified by the end of the 21st century, and rational therapies could be developed....
Topics
- DNA Mutational Analysis
- Genetic Diseases, Inborn
- Genetic Linkage
- Genetic Predisposition to Disease
- Genetic Techniques
- Genome, Human
- Genotype
- Humans
- Mutation
- Phenotype