Genetics of complex diseases.

doi:10.1631/jzus.2006.B0167

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Article

Genetics of complex diseases.

Journal of Zhejiang University. Science. B - 1 Feb 2006

Motulsky Arno G

Abstract excerpt

Approaches to the study of the genetic basis of common complex diseases and their clinical applications are considered. Monogenic Mendelian inheritance in such conditions is infrequent but its elucidation may help to detect pathogenic mechanisms in the more common variety of complex diseases. Involvement by multiple genes in complex diseases usually occurs but the isolation and identification of specific genes so...

Topics

Genetic Diseases, Inborn
Genetic Predisposition to Disease
Genetic Techniques
Humans
Inheritance Patterns
Linkage Disequilibrium
Models, Genetic
Polymorphism, Genetic
Risk Factors

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Identifiers

PMID: 16421979
DOI: 10.1631/jzus.2006.B0167
PMCID: PMC1363767

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