Article
Polymorphisms in the putative micro-RNA-binding sites of mesothelin gene are associated with serum levels of mesothelin-related protein.
Occupational and environmental medicine - 1 Apr 2010
Cristaudo Alfonso, Foddis Rudy, Bonotti Alessandra, Simonini Silvia, Vivaldi Agnese, Guglielmi Giovanni, Bruno Rossella, Landi Debora, Gemignani Federica, Landi Stefano
Abstract excerpt
BACKGROUND: Serum mesothelin, also known as soluble mesothelin-related protein (SMRP), reportedly shows increased levels in epithelial-type malignant pleural mesothelioma, but sometimes also arrives at high values in healthy asbestos-exposed subjects. OBJECTIVES: This study aimed to investigate whether single nucleotide polymorphisms in the 3'untranslated region (3'UTR) of the mesothelin-encoded gene (MSLN) are...
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