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Article

Evaluation of soluble mesothelin-related peptides and MSLN genetic variability in asbestos-related diseases.

Radiology and oncology - 7 Mar 2020

Goricar Katja, Kovac Viljem, Dodic-Fikfak Metoda, Dolzan Vita, Franko Alenka

Abstract excerpt

Background Asbestos exposure is associated with increased risk of several diseases, including malignant mesothelioma (MM). Cell surface glycoprotein mesothelin is overexpressed in MM and serum soluble mesothelin-related peptides (SMRP) were already proposed as a diagnostic or prognostic biomarker in MM. However, interindividual variability in serum SMRP levels limits the clinical usefulness. Our primary objective...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32187018
DOI: 10.2478/raon-2020-0011
PMCID: PMC7087423

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