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Article

Activated BRAF induces gliomas in mice when combined with Ink4a/Arf loss or Akt activation.

Oncogene - 21 Jan 2010

Robinson J P, VanBrocklin M W, Guilbeault A R, Signorelli D L, Brandner S, Holmen S L

Abstract excerpt

Mutations in receptor tyrosine kinase (RTK) growth factor receptors (epidermal growth factor receptor, platelet-derived growth factor receptor, MET and ERBB2), which result in downstream activation of the RAS/RAF/MEK/ERK mitogen-activated protein kinase (MAPK) pathway and PI(3)K/Akt pathway, are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19855433
DOI: 10.1038/onc.2009.333
PMCID: PMC4109991

Genes

BRAF
ERBB2
MET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19855433-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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