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Article

Pancreatic precursors and differentiated islet cell types from murine embryonic stem cells: an in vitro model to study islet differentiation.

Diabetes - 1 Aug 2003

Kahan Brenda W, Jacobson Lynn M, Hullett Debra A, Ochoada Jaime M, Oberley Terry D, Lang Katharine M, Odorico Jon S

Abstract excerpt

Embryonic stem (ES) cells differentiating in vitro reproduce many facets of early embryonic development, including the expression of developmentally regulated transcription factors and the differentiation of multipotent precursor cells. ES cells were evaluated for their ability to differentiate into pancreatic and islet lineage-restricted stages including pancreatic duodenal homeobox 1 (PDX1)-positive pancreatic...

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Identifiers

PMID: 12882918
DOI: 10.2337/diabetes.52.8.2016

Genes

PDX1
IAPP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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