Article
Prenatal acetaminophen exposure and risk of wheeze at age 5 years in an urban low-income cohort.
Thorax - 1 Feb 2010
Perzanowski Matthew S, Miller Rachel L, Tang Deliang, Ali David, Garfinkel Robin S, Chew Ginger L, Goldstein Inge F, Perera Frederica P, Barr R Graham
Abstract excerpt
BACKGROUND: Acetaminophen has been associated with asthma and is in part metabolised via the glutathione pathway. Inner-city minority children have high asthma morbidity and a relatively high frequency of a minor allele variant in the glutathione S transferase Pi gene (GSTP1). We hypothesised that prenatal acetaminophen exposure would predict wheeze at age 5 years in an inner-city minority cohort and examined...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.