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Article

Elastin-driven genetic diseases.

Matrix biology : journal of the International Society for Matrix Biology - 1 Oct 2018

Duque Lasio Maria Laura, Kozel Beth A

Abstract excerpt

Elastic fibers provide recoil to tissues that undergo repeated deformation, such as blood vessels, lungs and skin. Composed of elastin and its accessory proteins, the fibers are produced within a restricted developmental window and are stable for decades. Their eventual breakdown is associated with a loss of tissue resiliency and aging. Rare alteration of the elastin (ELN) gene produces disease by impacting...

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Source

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Identifiers

PMID: 29501665
DOI: 10.1016/j.matbio.2018.02.021
PMCID: PMC8409172

Genes

ELN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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