Article
Cognitive phenotypes, brain morphometry and the detection of cognitive decline in preclinical AD.
Behavioural neurology - 1 Jan 2009
Jacobson Mark W, McEvoy Linda K, Dale Anders, Fennema-Notestine Christine
Abstract excerpt
Identifying a preclinical phase of Alzheimer's Disease (PCAD) that is distinct from cognitive changes in healthy aging continues to be a major research focus. Combining neuropsychological and neuroimaging methodologies should improve our ability to differentiate healthy from pathological aging, although studies that utilize both methods often result in equivocal findings, possibly due to variability in cognitive...
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