Article
192R allele of paraoxanase 1 (PON1) gene as a new marker for susceptibility to bladder cancer.
Anticancer research - 1 Oct 2009
Oztürk Oğuz, Kağnici Omer F, Oztürk Tülin, Durak Haydar, Tüzüner Bora M, Kisakesen Halil I, Cakalir Canser, Isbir Turgay
Abstract excerpt
BACKGROUND: The human body has a number of endogenous free-radical scavenging systems. Paraoxonase1 (PON1) is one of the enzymes involved in such systems. The purpose of this study was to investigate the relationship between bladder cancer and the polymorphism of PON1 which results in Q/R substitution at codon 192. This is the first report of this polymorphism in bladder cancer. PATIENTS AND METHODS: Seventy-six...
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