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Article

Differential effects of paraoxonase 1 (PON1) polymorphisms on cancer risk: evidence from 25 published studies.

Molecular biology reports - 1 Jun 2012

Fang Dai-Hua, Fan Cong-Hai, Ji Qiang, Qi Bo-Xiang, Li Juan, Wang Lu

Abstract excerpt

Paraoxonase is an HDL-associated enzyme that plays a preventive role against oxidative stress, which is thought to contribute to cancer development. PON1 activity varies widely among individuals, which is in part related to two common nonsynonymous polymorphisms in the PON1 gene (Q192R and L55M). The polymorphisms in PON1 have been implicated in cancer risk. However, results from the studies to date have been...

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PMID: 22322559
DOI: 10.1007/s11033-012-1505-3

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential effects of paraoxonase 1 (PON1) polymorphisms on cancer risk: evidence from 25 published studies.PMID 22322559Read ↗

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