Article
Is paraoxonase 192 gene polymorphism a risk factor for membranoproliferative glomerulonephritis in children?
Cell biochemistry and function - 1 Jan 2000
Bilge Ilmay, Sirin Aydan, Agachan Bedia, Emre Sevinc, Sadikoglu Banu, Yilmaz Hülya, Sucu Aysegül, Isbir Turgay
Abstract excerpt
We investigated the effects of paraoxonase (PON1) 192 polymorphism on serum PON1 activity and the impact of phenotypic expression on the risk and prognosis of Turkish children with membranoproliferative glomerulonephritis (MPGN). Eighteen children with biopsy-proven Type I MPGN (10 boys, 8 girls) and age-matched 53 healthy controls were included in the study. PCR (polymerase chain reaction), RFLP (restriction...
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