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Article

Q192R variant in paraoxonase 1 gene confers susceptibility to leiomyoma.

Journal of cancer research and therapeutics - 1 Jan 2000

Shahbazi Shirin, Zarei Soghra, Torfeh Mahnaz, Fatahi Neda

Abstract excerpt

OBJECTIVE: Paraoxonase 1 (PON1) plays a defensive role against oxidative stress by destroying oxidized lipids. Q192R single nucleotide polymorphism of PON1 gene alters the enzyme's activity. Several investigations reported a link between Q192R and an increased risk of developing tumors including uterine leiomyomas. We assessed the antioxidant effects of Q192R on myoma which fluctuate in frequency between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32930135
DOI: 10.4103/jcrt.JCRT_923_16

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Q192R variant in paraoxonase 1 gene confers susceptibility to leiomyoma.PMID 32930135Read ↗

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