Article
Muscle contractions guide rohon-beard peripheral sensory axons.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Oct 2009
Paulus Jeremiah D, Willer Gregory B, Willer Jason R, Gregg Ronald G, Halloran Mary C
Abstract excerpt
Multiple molecular cues guide neuronal axons to their targets during development. Previous studies in vitro have shown that mechanical stimulation also can affect axon growth; however, whether mechanical force contributes to axon guidance in vivo is unknown. We investigated the role of muscle contractions in the guidance of zebrafish peripheral Rohon-Beard (RB) sensory axons in vivo. We analyzed several mutants...
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