Article
Lack of association between TNF-alpha promoter polymorphism and prostate carcinoma susceptibility in eastern Croatian population.
Collegium antropologicum - 1 Dec 2013
Horvat Vesna, Sudarević Bojan, Cosić Ivan, Milicević Nevenka, Bosnjak Silvana, Mandić Sanja, Marczi Saska, Simunović Dalibor, Galić Josip
Abstract excerpt
A single nuclear polymorphisms (SNPs) in the promoter region of the tumor necrosis factor-alpha (TNF-alpha) gene are involved in regulation of expression levels of TNF-alpha and therefore are associated with oncogenesis of several cancers. Aim of our study was to investigate the effect of G--->A polymorphism at -308 position in the promoter region of the TNF-alpha gene on prostate cancer (CalphaP) susceptibility...
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