Article
Exercise-induced ECG changes in Brugada syndrome.
Circulation. Arrhythmia and electrophysiology - 1 Oct 2009
Amin Ahmad S, de Groot Elisabeth A A, Ruijter Jan M, Wilde Arthur A M, Tan Hanno L
Abstract excerpt
BACKGROUND: Ventricular arrhythmia occurrence during exercise is reported in Brugada syndrome (BrS). Accordingly, experimental studies suggest that BrS-linked SCN5A mutations reduce sodium current more at fast heart rates. Yet, the effects of exercise on the BrS ECG phenotype have not been studied. We aimed to assess ECG responses to exercise in BrS and determine whether these responses are affected by the...
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