Article
Distinct expression patterns of dickkopf genes during late embryonic development of Danio rerio.
Gene expression patterns : GEP - 1 Dec 2011
Untergasser Gerold, Martowicz Agnieszka, Hermann Martin, Töchterle Sonja, Meyer Dirk
Abstract excerpt
Dickkopf (dkk) genes belong to the family of secreted wnt-inhibitors with conserved cysteine-rich domains. In contrast to the prototype dkk1, dkk3 does not modulate canonical Wnt/β-catenin signalling. Until now, neither functions nor interaction partners of dkk3 in lower vertebrates have been described. In this study we cloned two dkk3 homologues dkk3a(dkk3l) and dkk3b(dkk3) and a dkk1 homologue dkk1a of the...
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