Article
Influenza A gradual and epochal evolution: insights from simple models.
PloS one - 20 Oct 2009
Ballesteros Sébastien, Vergu Elisabeta, Cazelles Bernard
Abstract excerpt
The recurrence of influenza A epidemics has originally been explained by a "continuous antigenic drift" scenario. Recently, it has been shown that if genetic drift is gradual, the evolution of influenza A main antigen, the haemagglutinin, is punctuated. As a consequence, it has been suggested that influenza A dynamics at the population level should be approximated by a serial model. Here, simple models are used...
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