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Article

Glutathione S-transferase gene deletions and their effect on iron status in HbE/beta thalassemia patients.

Annals of hematology - 1 Apr 2010

Sharma Vineeta, Kumar Bijender, Saxena Renu

Abstract excerpt

Iron overload and oxidative stress are main pathophysiological features of HbE/beta thalassemia patients. Glutathione S-transferase genes (GSTT1 and GSTM1) are well known detoxification agents, and any mutation in the gene is known to cause oxidative damage. This study was aimed to compare the prevalence of GST deletions in 240 HbE/beta thalassemia patients with 100 controls and to determine role of deletions on...

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Source

Identifiers

PMID: 19838709
DOI: 10.1007/s00277-009-0847-y

Genes

GSTT1
GSTM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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