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Article

Glutathione S-transferase M1 gene polymorphisms are associated with cardiac iron deposition in patients with beta-thalassemia major.

Hemoglobin - 1 Jan 2006

Wu Kang-Hsi, Chang Jan-Gowth, Ho Yung-Jen, Wu Shu-Fen, Peng Ching-Tien

Abstract excerpt

Patients with beta-thalassemia (thal) major are subject to peroxidative tissue injury by iron overload. Glutathione S-transferases work as antioxidants, and their activity is determined genetically. In this study, we used multiplex polymerase chain reaction (m-PCR) to analyze polymorphisms of two endogenous antioxidant agents, glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1), and to...

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Source

Identifiers

PMID: 16798650
DOI: 10.1080/03630260600642575

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Glutathione S-transferase M1 gene polymorphisms are associated with cardiac iron deposition in patients with beta-thalassemia major.PMID 16798650Read ↗

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The relation between glutathione S-Transferase M1 null-genotype and cardiac problems in beta-thalassemia.Semantic proximity Read ↗

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