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Article

GST M1/T1 and MTHFR polymorphisms as risk factors for hypertension.

Biochemical and biophysical research communications - 9 Feb 2007

Marinho Cláudia, Alho Irina, Arduíno Daniela, Falcão Luiz Menezes, Brás-Nogueira José, Bicho Manuel

Abstract excerpt

The aim of this study is to investigate GSTM1, GSTT1 and MTHFR genetic polymorphisms and its relation with total plasma glutathione (tGSH) levels in hypertension. Genotype distributions of GSTM1 and GSTT1 deletion polymorphisms and C677T variant of MTHFR were examined in a sample of 94 hypertensive patients with congestive heart failure and 207 healthy unrelated Portuguese individuals using PCR techniques. Plasma...

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DNA Mutational Analysis
Genetic Testing
Glutathione Transferase
Hypertension
New York

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Risk Assessment

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Identifiers

PMID: 17182005
DOI: 10.1016/j.bbrc.2006.12.019

Genes

GSTT1
MTHFR
GSTM1

Variants

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