Article
Association of the single nucleotide polymorphism rs599839 in the vicinity of the sortilin 1 gene with LDL and triglyceride metabolism, coronary heart disease and myocardial infarction. The Ludwigshafen Risk and Cardiovascular Health Study.
Atherosclerosis - 1 Apr 2010
Kleber Marcus E, Renner Wilfried, Grammer Tanja B, Linsel-Nitschke Patrick, Boehm Bernhard O, Winkelmann Bernhard R, Bugert Peter, Hoffmann Michael M, März Winfried
Abstract excerpt
OBJECTIVE: The rs599839 polymorphism A/G in the vicinity of the sortilin 1 gene has been reported to be associated with low density lipoprotein cholesterol (LDL-C) and coronary artery disease (CAD). The objective of this study was to further characterize the protective effect of the minor allele by analyzing the association with a variety of quantitative traits. METHODS: Association of rs599839 with plasma levels...
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