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Article

Toll-like receptors and chronic lung disease

25 Jul 2005

Abstract excerpt

TLRs (Toll-like receptors) comprise a family of proteins whose function is principally to facilitate the detection of, and response to, pathogens. Protozoa, helminths, viruses, bacteria and fungi can all activate TLR signalling, and these signals have important roles in the activation of host defence. TLRs may also respond to products of tissue damage, providing them with roles in infective and sterile...

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PMID: 16033327
DOI: 10.1042/cs20050044

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