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Article

[Mutator hypothesis of carcinogenesis and supermutagens in anticancer therapy].

Vestnik Rossiiskoi akademii meditsinskikh nauk - 1 Jan 2009

Krutiakov V M

Abstract excerpt

The putative causative relationship between mutator nature of carcinogenesis and positive results of empirical application of supermutagens for anticancer therapy is discussed. Part 1 of the review is devoted to the substantiation of the mutator theory of carcinogenesis. Part 2 provides an explanation of positive results of empirical application of supermutagens for anticancer therapy in the framework of this theory.

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PMID: 19827641

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