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Article

Appetitively motivated instrumental learning in SynGAP heterozygous knockout mice.

Behavioral neuroscience - 1 Oct 2009

Muhia Mary, Feldon Joram, Knuesel Irene, Yee Benjamin K

Abstract excerpt

The synaptic Ras/Rap-GTPase-activating protein (SynGAP) regulates specific intracellular events following N-methyl-d-aspartate receptor (NMDAR) activation. Here, the impact of SynGAP heterozygous knockout (SG+/-) on NMDAR-dependent functions was assessed using different positive reinforcement schedules in instrumental conditioning. The knockout did not affect the temporal control of operant responding under a...

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Identifiers

PMID: 19824778
DOI: 10.1037/a0017118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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