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Article

Impact of androgen receptor cytosine-adenine-guanine polymorphisms on clinical outcome in BRCA mutation-associated epithelial ovarian cancers.

Gynecologic oncology - 1 Jan 2010

Li Andrew J, McAllister Paula, Karlan Beth Y

Abstract excerpt

PURPOSE: Androgen signaling may function in the pathobiology of epithelial ovarian cancers associated with mutations in the BRCA1/2 genes. Androgen receptor (AR) activity correlates inversely with length of a polymorphic cytosine-adenine-guanine (CAG) repeat in exon 1. We hypothesized that AR CAG allele length is a modifier of clinical outcome in BRCA1/2 mutation positive women with ovarian cancer. EXPERIMENTAL...

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Share to Epithelial Cells
Share to Genes, BRCA1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Germ-Line Mutation

Share to Neoplasm Staging

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Share to Receptors, Androgen

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 19818997
DOI: 10.1016/j.ygyno.2009.09.020

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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