Article
Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2007
Schildkraut Joellen M, Murphy Susan K, Palmieri Rachel T, Iversen Edwin, Moorman Patricia G, Huang Zhiqing, Halabi Susan, Calingaert Brian, Gusberg Alison, Marks Jeffrey R, Berchuck Andrew
Abstract excerpt
INTRODUCTION: Androgens may play a role in the development of ovarian cancers. Two trinucleotide repeat polymorphisms have been described in exon 1 of the androgen receptor (AR) gene that may affect its function. Previous studies of ovarian cancer and AR repeat polymorphisms have been inconsistent. METHODS: We analyzed CAG and GGC repeat length polymorphisms in the AR gene using data from a population-based...
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