Progenitor cells from the explanted heart generate immunocompatible myocardium within the transplanted donor heart.

doi:10.1161/CIRCRESAHA.109.207266

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Progenitor cells from the explanted heart generate immunocompatible myocardium within the transplanted donor heart.

Circulation research - 20 Nov 2009

D'Alessandro David A, Kajstura Jan, Hosoda Toru, Gatti Alessandro, Bello Ricardo, Mosna Federico, Bardelli Silvana, Zheng Hanqiao, D'Amario Domenico, Padin-Iruegas M Elena, Carvalho Adriana Bastos, Rota Marcello, Zembala Michael O, Stern David, Rimoldi Ornella, Urbanek Konrad, Michler Robert E, Leri Annarosa, Anversa Piero

Abstract excerpt

RATIONALE: Chronic rejection, accelerated coronary atherosclerosis, myocardial infarction, and ischemic heart failure determine the unfavorable evolution of the transplanted heart in humans. OBJECTIVE: Here we tested whether the pathological manifestations of the transplanted heart can be corrected partly by a strategy that implements the use of cardiac progenitor cells from the recipient to repopulate the donor...

Topics

Animals
Base Sequence
Cell Differentiation
Cell Fusion
Coronary Vessels
Dogs
Female
Genotype
Graft Rejection

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Green Fluorescent Proteins

Heart Failure

Heart Transplantation

Histocompatibility

Immunosuppressive Agents

Male

Molecular Sequence Data

Myocardium

Myocytes, Cardiac

Source

Open in PubMed Open full text

Identifiers

PMID: 19815820
DOI: 10.1161/CIRCRESAHA.109.207266
PMCID: PMC2801080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Progenitor cells from the explanted heart generate immunocompatible myocardium within the transplanted donor heart.PMID 19815820Read ↗

The Elusive Progenitor Cell in Cardiac RegenerationSemantic proximity Read ↗

<i>In vivo</i> generation of heart and vascular system by blastocyst complementationSemantic proximity Read ↗

Bone marrow cells for cardiac regeneration and repair: current status and issues.Semantic proximity Read ↗

Hypoimmune induced pluripotent stem cell–derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic miceSemantic proximity Read ↗

Animal models to study cardiac regenerationSemantic proximity Read ↗

Cord lining-mesenchymal stem cells graft supplemented with an omental flap induces myocardial revascularization and ameliorates cardiac dysfunction in a rat model of chronic ischemic heart failure.Semantic proximity Read ↗

MHC-mismatched Allotransplantation of Induced Pluripotent Stem Cell-derived Cardiomyocyte Sheets to Improve Cardiac Function in a Primate Ischemic Cardiomyopathy ModelSemantic proximity Read ↗

Progress Toward Cardiac XenotransplantationSemantic proximity Read ↗

Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarctionSemantic proximity Read ↗

Heart grafts tolerized through third-party multipotent adult progenitor cells can be retransplanted to secondary hosts with no immunosuppression.Semantic proximity Read ↗

Characterization of long-term endogenous cardiac repair in children after heart transplantation.Semantic proximity Read ↗

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular TachyarrhythmiasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.