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Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction

6 Oct 2003

Abstract excerpt

Potential repair by cell grafting or mobilizing endogenous cells holds particular attraction in heart disease, where the meager capacity for cardiomyocyte proliferation likely contributes to the irreversibility of heart failure. Whether cardiac progenitors exist in adult myocardium itself is unanswered, as is the question whether undifferentiated cardiac precursor cells merely fuse with preexisting myocytes. Here...

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PMID: 14530411
DOI: 10.1073/pnas.2132126100

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