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Article

CT60 and +49 polymorphisms of CTLA 4 are associated with ANCA-positive small vessel vasculitis.

Rheumatology (Oxford, England) - 1 Dec 2009

Kamesh Lavanya, Heward Joanne M, Williams Julie M, Gough Stephen C L, Chavele Konstantia-Maria, Salama Alan, Pusey Charles, Savage Caroline O S, Harper Lorraine

Abstract excerpt

OBJECTIVE: To investigate whether single nucleotide polymorphisms (SNPs) within cytotoxic T-lymphocyte antigen-4 (CTLA-4) are associated with ANCA-associated small vessel vasculitis (SVV). METHODS: The CTLA-4 CT60 (exon 4), +49 (exon 1) and -318 (promoter region) genotypes were determined by PCR and restriction fragment length polymorphism (RFLP) in 222 white Caucasians of UK origin with SVV and 670 ethnically...

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Identifiers

PMID: 19815671
DOI: 10.1093/rheumatology/kep280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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