Article
Caveolin-1 single nucleotide polymorphism in antineutrophil cytoplasmic antibody associated vasculitis.
PloS one - 1 Jan 2013
Chand Sourabh, Holle Julia U, Hilhorst Marc, Simmonds Matthew J, Smith Stuart, Kamesh Lavanya, Hewins Peter, McKnight Amy Jayne, Maxwell Alexander P, Cohen Tervaert Jan Willem, Wieczorek Stefan, Harper Lorraine, Borrows Richard
Abstract excerpt
OBJECTIVE: Immunosuppression is cornerstone treatment of antineutrophil cytoplasmic antibody associated vasculitis (AAV) but is later complicated by infection, cancer, cardiovascular and chronic kidney disease. Caveolin-1 is an essential structural protein for small cell membrane invaginations kn...
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