Article
Association of PTPN22 C1858T and CTLA-4 A49G polymorphisms with Type 1 Diabetes in Croatians.
Diabetes research and clinical practice - 1 Dec 2009
Korolija Marina, Renar Ivana Pavlić, Hadzija Mirko, Medvidović Edita Pape, Pavković Pajica, Jokić Mladen, Hadzija Marijana Popović
Abstract excerpt
In this case-control study the association between the PTPN22 1858T and CTLA-4 49G gene variants and T1D in Croatian population was examined. We found that distribution of PTPN22 C1858T and CTLA-4 A49G genotypes between T1D patient (n=102) and control (n=193) groups differ significantly (p<0.0001 and p=0.012, respectively). Moreover, although the risk alleles of both SNPs are distributed more frequently in...
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