Article
Large-scale search of single nucleotide polymorphisms for hepatocellular carcinoma susceptibility genes in patients with hepatitis C.
Hepatology (Baltimore, Md.) - 1 Oct 2005
Kato Naoya, Ji Guijin, Wang Yue, Baba Masanori, Hoshida Yujin, Otsuka Motoyuki, Taniguchi Hiroyoshi, Moriyama Masaru, Dharel Narayan, Goto Tadashi, Shao Run-Xuan, Matsuura Tadashi, Ishii Keisuke, Shiina Shuichiro, Kawabe Takao, Muramatsu Masaaki, Omata Masao
Abstract excerpt
Hepatitis C virus (HCV) infection is a major risk factor for developing hepatocellular carcinoma (HCC). The host genetic factors that are involved in the development of HCC in patients with HCV infection remain to be investigated. To search for single nucleotide polymorphisms (SNPs) in HCC susceptibility genes, 393 SNPs in 171 candidate genes were examined in 188 Japanese patients with chronic HCV infection,...
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