Article
Association of a variant in MIR 196A2 with susceptibility to hepatocellular carcinoma in male Chinese patients with chronic hepatitis B virus infection.
Human immunology - 1 Jun 2010
Qi Peng, Dou Tong-hai, Geng Li, Zhou Fei-guo, Gu Xing, Wang Hao, Gao Chun-fang
Abstract excerpt
MicroRNAs (miRNAs) are small noncoding RNAs with regulatory functions as tumor suppressors and oncogenes. Recent studies have implicated that the rs11614913 SNP in MIR196A2 was associated with susceptibility of lung cancer, congenital heart disease, breast cancer and shortened survival time of nonsmall cell lung cancer. To assess whether this polymorphism is associated with susceptibility to and clinicopathologic...
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