Article
Common variants on chromosome 2 and risk of primary open-angle glaucoma in the Afro-Caribbean population of Barbados.
Proceedings of the National Academy of Sciences of the United States of America - 6 Oct 2009
Jiao Xiaodong, Yang Zhenglin, Yang Xian, Chen Yuhong, Tong Zongzhong, Zhao Chao, Zeng Jiexi, Chen Haoyu, Gibbs Daniel, Sun Xufang, Li Bei, Wakins W Scott, Meyer Cynthia, Wang Xiaolei, Kasuga Daniel, Bedell Matthew, Pearson Erik, Weinreb Robert N, Leske M Cristina, Hennis Anselm, DeWan Andrew, Nemesure Barbara, Jorde Lynn B, Hoh Josephine, Hejtmancik J Fielding, Zhang Kang
Abstract excerpt
Primary open-angle glaucoma (POAG) is the second leading cause of blindness worldwide. Although a number of genetic loci have shown association or genetic linkage to monogenic forms of POAG, the identified genes and loci do not appear to have a major role in the common POAG phenotype. We seek to identify genetic loci that appear to be major risk factors for POAG in the Afro-Caribbean population of Barbados, West...
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