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Article

Investigation of known genetic risk factors for primary open angle glaucoma in two populations of African ancestry.

Investigative ophthalmology & visual science - 17 Sept 2013

Liu Yutao, Hauser Michael A, Akafo Stephen K, Qin Xuejun, Miura Shiroh, Gibson Jason R, Wheeler Joshua, Gaasterland Douglas E, Challa Pratap, Herndon Leon W, Ritch Robert, Moroi Sayoko E, Pasquale Louis R, Girkin Christopher A, Budenz Donald L, Wiggs Janey L, Richards Julia E, Ashley-Koch Allison E, Allingham R Rand

Abstract excerpt

PURPOSE: Multiple genes have been associated with primary open angle glaucoma (POAG) in Caucasian populations. We now examine the association of these loci in populations of African ancestry, populations at particularly high risk for POAG. METHODS: We genotyped DNA samples from two populations: African American (1150 cases and 999 controls) and those from Ghana, West Africa (483 cases and 593 controls). Our...

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Source

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Identifiers

PMID: 23963167
DOI: 10.1167/iovs.13-12779
PMCID: PMC3776712

Genes

SIX1
SIX6
CAV1
CAV2
TMCO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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