Article
The Role of Genetic Ancestry as a Risk Factor for Primary Open-angle Glaucoma in African Americans.
Investigative ophthalmology & visual science - 1 Feb 2021
Cole Brian S, Gudiseva Harini V, Pistilli Maxwell, Salowe Rebecca, McHugh Caitlin P, Zody Michael C, Chavali Venkata R M, Ying Gui Shuang, Moore Jason H, O'Brien Joan M
Abstract excerpt
Purpose: POAG is the leading cause of irreversible blindness in African Americans. In this study, we quantitatively assess the association of autosomal ancestry with POAG risk in a large cohort of self-identified African Americans. Methods: Subjects recruited to the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study were classified as glaucoma cases or controls by fellowship-trained glaucoma...
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