Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LRRK2 in Parkinson's disease: in vivo models and approaches for understanding pathogenic roles.

The FEBS journal - 1 Nov 2009

Yue Zhenyu

Abstract excerpt

The recent discovery of the genetic causes for Parkinson's disease (PD) is fruitful; however, the continuing revelation of PD-related genes is rapidly outpacing the functional characterization of the gene products. Although the discovery of multiple PD-related genes places PD as one of the most complex multigenetic diseases of the brain, it will undoubtedly facilitate the unfolding of a central pathogenic pathway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Share to Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Parkinson Disease

Share to Protein Serine-Threonine Kinases

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 19804414
DOI: 10.1111/j.1742-4658.2009.07343.x
PMCID: PMC2827245

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LRRK2 in Parkinson's disease: in vivo models and approaches for understanding pathogenic roles.PMID 19804414Read ↗

Roles of LRRK2 and its orthologs in protecting against neurodegeneration and neurodevelopmental defectsSemantic proximity Read ↗

Genetic LRRK2 models of Parkinson's disease: Dissecting the pathogenic pathway and exploring clinical applications.Semantic proximity Read ↗

Modelling the functional genomics of Parkinson's disease in Caenorhabditis elegans: LRRK2 and beyond.Semantic proximity Read ↗

LRRK2 and Parkinson disease.Semantic proximity Read ↗

Dispensable role of Drosophila ortholog of LRRK2 kinase activity in survival of dopaminergic neuronsSemantic proximity Read ↗

Leucine‐rich repeat kinase 2 and Parkinson's diseaseSemantic proximity Read ↗

Targeting LRRK2 in Parkinson's disease: an update on recent developments.Semantic proximity Read ↗

LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's diseaseSemantic proximity Read ↗

Investigating Convergent Actions of Genes Linked to Familial Parkinson’s DiseaseSemantic proximity Read ↗

LRRK2 pathobiology in Parkinson's disease.Semantic proximity Read ↗

The neurobiology of LRRK2 and its role in the pathogenesis of Parkinson's disease.Semantic proximity Read ↗

Cellular processes associated with LRRK2 function and dysfunction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.