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Article

HEY1 Leu94Met gene polymorphism dramatically modifies its biological functions.

Oncogene - 21 Jan 2010

Villaronga M A, Lavery D N, Bevan C L, Llanos S, Belandia B

Abstract excerpt

The hairy/enhancer-of-split related with YRPW motif 1 (HEY1) is a member of the basic-helix-loop-helix-Orange (bHLH-O) family of transcriptional repressors that mediate Notch signaling. Several cancer-related pathways also regulate HEY1 expression, and HEY1 itself acts as an indirect positive reg...

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Source

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Identifiers

PMID: 19802006
DOI: 10.1038/onc.2009.309
PMCID: PMC3381846

Genes

HEY1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19802006-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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