Article
Adrenergic beta(2)-receptor genotype predisposes to exacerbations in steroid-treated asthmatic patients taking frequent albuterol or salmeterol.
The Journal of allergy and clinical immunology - 1 Dec 2009
Basu Kaninika, Palmer Colin N A, Tavendale Roger, Lipworth Brian J, Mukhopadhyay Somnath
Abstract excerpt
BACKGROUND: On-demand inhaled albuterol is commonly prescribed worldwide. We have shown that the Arg16 allele of the adrenergic beta(2)-receptor agonist gene (ADRB2) predisposes to exacerbations in young asthmatic patients taking regular salmeterol. OBJECTIVE: We have now extended our previous population by 636 patients and explored the role of the Arg16 allele on asthma exacerbations in the context of the use of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
