Article
Association between Gc genotype and susceptibility to TB is dependent on vitamin D status.
The European respiratory journal - 1 May 2010
Martineau A R, Leandro A C C S, Anderson S T, Newton S M, Wilkinson K A, Nicol M P, Pienaar S M, Skolimowska K H, Rocha M A, Rolla V C, Levin M, Davidson R N, Bremner S A, Griffiths C J, Eley B S, Bonecini-Almeida M G, Wilkinson R J
Abstract excerpt
Group-specific component (Gc) variants of vitamin D binding protein differ in their affinity for vitamin D metabolites that modulate antimycobacterial immunity. We conducted studies to determine whether Gc genotype associates with susceptibility to tuberculosis (TB). The following subjects were r...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.