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Article

Vitamin D deficiency associates with susceptibility to tuberculosis in Pakistan, but polymorphisms in VDR, DBP and CYP2R1 do not.

BMC pulmonary medicine - 10 May 2016

Junaid Kashaf, Rehman Abdul, Jolliffe David A, Saeed Tahir, Wood Kristie, Martineau Adrian R

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) in the genes encoding the vitamin D receptor (VDR) and the vitamin D binding protein (DBP) have been reported to modify the influence of vitamin D deficiency on susceptibility to active tuberculosis (TB) in the UK, but this phenomenon has not been investigated in settings with a high TB burden. SNPs in CYP2R1, which encodes a vitamin D 25-hydroxylase enzyme, are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27160686
DOI: 10.1186/s12890-016-0240-2
PMCID: PMC4862192

Genes

DBP
VDR

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